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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28626 | Rutamycin | Oligomycin D,A272,A 272,A-272 | |
Rutamycin is a macrolide antibiotic of the oligomycin group obtained from Streptomyces rutgersensis. It inhibits various ATPases and uncouples oxidative phosphorylation from electron transport. | |||
T7194 | CM-272 | Apoptosis , DNA Methyltransferase , Histone Methyltransferase | |
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor. | |||
T27595 | Imarikiren HCl | TAK-272 hydrochloride,TAK-272 HCl. Imarikiren HCl |,TAK272,TAK 272,TAK-272 | |
Imarikiren is a potent, selective and orally active direct renin inhibitor. TAK-272 shows potent inhibitory activity against human renin (IC50 = 2.1 nM) in hPRA assay and excellent selectivity against other aspartic prot... | |||
T29812 | AL-272 | AL 272 | |
AL-272 is a bio-active chemical. | |||
T27737 | KNI-272 | NSC-651714,Kynostatin-272,Kynostatin272,KNI272,Kynostatin 272 | |
Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles. | |||
T15400 | GNE-272 | Epigenetic Reader Domain | |
GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300. | |||
T10215 | AAPK-25 | Apoptosis , PLK , Aurora Kinase | |
AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in prometaphase, followed by a surge in apoptosis. AAPK-25 targets Aurora-A/-B/-C with ... | |||
T36781 | St-Ht31 P | st-Ht31 P | |
Negative control for st-Ht31 . Gorshkov et al (2017) AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nat.Chem.Biol. 13 425 PMID:28192412 |Vijayaraghavan et al (1997) Protein kinase A-a... | |||
T35776 | Janthitrem A | ||
Janthitrem A is a mycotoxin that has been found inP. janthinellum.1It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg.2Janthitrem A (20 μg/g) also reducesW. ... | |||
T36346 | Ac-VEID-AMC (ammonium acetate salt) | ||
Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis.1It has also been reported to be cleaved by related proteases, including caspase-8.2Caspase acti... | |||
T37690 | Phenylpyropene A | ||
Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).... |